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Analysis finds lower IQ in children with chronic kidney disease
22 Feb 2018 at 2:14pm
An analysis of published studies indicates that children with chronic kidney disease may have lower intellectual functioning compared than children in the general population. Compared with children with mild-to-moderate stage kidney disease and with kidney transplants, children on dialysis had the lowest IQ scores. Deficits were evident for attention, memory, and executive function domains.

Sweet, bitter, fat: Genetics play a role in kids' snacking patterns
22 Feb 2018 at 1:21pm
The types of snacks a child chooses could be linked to genetics, a new study found. The study investigated whether genetic variants in taste receptors related to sweet, fat and bitter tastes influence the snacks preschoolers choose and found nearly 80 per cent carried at least one of these genotypes that could predispose them to poor snacking habits. These findings could help parents tailor their kids' diets based on their genetics of taste.


New crystal structures reveal mysterious mechanism of gene regulation by the ...
22 Feb 2018 at 1:21pm
Using an innovative crystallization technique for studying 3D structures of gene transcription machinery, researchers revealed new insights into the long debated action of the 'magic spot' -- a molecule that controls gene expression in E. coli and many other bacteria when the bacteria are stressed. The study contributes to fundamental understanding of how bacteria adapt and survive under adverse conditions and provides clues about key processes that could be targeted in the search for new antibiotics.

DNA gets away: Scientists catch the rogue molecule that can trigger autoimmunity
22 Feb 2018 at 11:51am
A research team has discovered the process -- and filmed the actual moment -- that can change the body's response to a dying cell. Importantly, what they call the 'Great Escape' moment may one day prove to be the crucial trigger for autoimmune diseases like arthritis.

Positive results for larotrectinib against TRK-fusion cancer
22 Feb 2018 at 11:50am
55 patients representing 17 cancer types tested positive for TRK fusion and were treated with larotrectinib. Overall response rate was 75 percent.

Looking for the origins of schizophrenia
22 Feb 2018 at 11:50am
Schizophrenia may be related to neurodevelopment changes, including brain's inability to create the appropriate vascular system, according to new study. The results broaden the understanding about the causes of this severe and disabling disorder, which affects about 1 percent of the world's population.


In living color: Seeing cells from outside the body with synthetic biolumines...
22 Feb 2018 at 11:50am
Glowing creatures like fireflies and jellyfish are captivating to look at but also a boon for science, as their bioluminescent molecules contribute to visualizing a host of biological processes. Now, scientists have supercharged these molecules, making them hundreds of times brighter in deep tissues and allowing for imaging of cells from outside the body. The bioengineered light source was used to track cancer cells in mice and brain-cell activity in monkeys, but its applications extend beyond the lab.

Loops, loops, and more loops: This is how your DNA gets organized
22 Feb 2018 at 11:50am
A living cell is able to neatly package a big jumble of DNA into chromosomes while preparing for cell division. For over a century, scientists have been puzzled for decades on how the process works. Researchers now managed for the first time to isolate and film the process, and witnessed -- in real time -- how a single protein complex called condensin reels in DNA to extrude a loop.


Gut microbes protect against sepsis: Mouse study
22 Feb 2018 at 11:50am
Sepsis occurs when the body's response to the spread of bacteria or toxins to the bloodstream damages tissues and organs. The fight against sepsis could get a helping hand from a surprising source: gut bacteria. Researchers found that giving mice particular microbes increased blood levels of immunoglobulin A (IgA) antibodies, which protected against the kind of widespread bacterial invasion that leads to sepsis.

A look at the space between mouse brain cells
22 Feb 2018 at 11:50am
Between the brain's neurons and glial cells is a critical but understudied structure that's been called neuroscience's final frontier: the extracellular space. With a new imaging paradigm, scientists can now see into and study this complex fluid-filled matrix.


New symmetry-breaking method opens way for bioactive compounds
22 Feb 2018 at 9:57am
Chemists have developed a new catalytic method for symmetry breaking. The method can help synthesize important building blocks for bioactive compounds such as anticancer drugs.


Neuroscientists discover a brain signal that indicates whether speech has bee...
22 Feb 2018 at 9:57am
The presence or absence of a unique brain signal after a listener has heard some speech indicates whether or not that listener has understood what has been said. The discovery has a number of practical applications, including tracking language development, assessing brain function post-injury, and confirming whether important instructions have been understood in high-pressure jobs.

Reprogramming adult cells into induced pluripotency with unprecedented effici...
22 Feb 2018 at 9:57am
A team of scientists has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

Could interneuron migration explain macrocephaly?
22 Feb 2018 at 9:57am
Researchers have discovered a new crosstalk between the migrating inhibitory interneurons and the stem cells that generate the excitatory neurons. The researchers discovered that this cellular dialogue controls the growth of the cerebral cortex and that its impairment leads a cortical malformation previously associated with autism in mice.

Color of judo uniform has no effect on winning
22 Feb 2018 at 9:57am
Contrary to previous studies and widespread belief, new research on competitive judo data finds a winning bias for the athlete who is first called, regardless of the color of their uniform.



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