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Study gives animal testing alternatives a confidence boost
17 May 2022 at 6:04pm
As part of a government effort to reduce animal testing, researchers have worked to produce a new protocol for screening skin allergens. The method is potentially cheaper and faster than animal testing, while maintaining a similar performance.

Timing of heart surgery crucial, research shows
17 May 2022 at 6:04pm
The timing of valve replacement heart surgery is crucial, and should be performed earlier than previously thought for people with aortic stenosis, a new study shows. The condition is one of the most common and serious valve disease problems, caused by a narrowing of the aortic valve opening.

Chemists skew the odds to prevent cancer
17 May 2022 at 2:02pm
A theoretical framework shows how to increase the odds of identifying cancer-causing mutations before tumors take hold. Researchers demonstrate that only a few energetically favorable pathways are likely to lead to cancer.

New protein structures to aid rational drug design
17 May 2022 at 2:02pm
In a major advance for rational drug design, chemists have described several protein structures of a crucial player in cellular processes. The advance could bring new ideas for treatments of diseases such as Alzheimer's, AIDS, cancer and others.

If you take several medications, 'polypharmacy' is a word to know
17 May 2022 at 12:46pm
Taking multiple prescription drugs and supplements can be fraught with risk, a new study suggests -- but it's hard for many people to part with their medications.

mRNA vaccines like Pfizer and Moderna fare better against COVID-19 variants o...
17 May 2022 at 12:18pm
A comparison of four COVID-19 vaccinations shows that messenger RNA (mRNA) vaccines -- Pfizer-BioNTech and Moderna -- perform better against the World Health Organization's variants of concern (VOCs) than viral vector vaccines -- AstraZeneca and J&J/Janssen. Although they all effectively prevent severe disease by VOCs, the research suggests that people receiving a viral vector vaccine are more vulnerable to infection by new variants.

Concussion symptoms in children may have multiple underlying causes
17 May 2022 at 12:18pm
Different types of brain damage caused by a concussion may lead to similar symptoms in children, according to new research. A new way of studying concussions could help develop future treatments.

Type-I interferon stops immune system 'going rogue' during viral infections
17 May 2022 at 12:18pm
Researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from 'going rogue' and attacking the body's own organs. This opens the way to potential new treatments that can save many lives.

Protein linked to intellectual disability has complex role
17 May 2022 at 8:23am
Researchers have identified a previously unknown function for the fragile X protein, the loss of which is the leading inherited cause of intellectual disability. The researchers showed that the protein modulates how neurons in the brain's memory center process information, a central part of learning and memory.

Scientists nail down 'destination' for protein that delivers zinc
17 May 2022 at 8:22am
New research describes a 'chaperone' protein that delivers zinc, a trace element essential for survival in all living things, to where it's needed. The chaperone could be especially important when access to zinc is limited -- for example in nutrient deficient diets and for growing crops on depleted soils.

How is it possible to remember selfless experiences?
17 May 2022 at 8:22am
People who practice intensive meditation report memories of states in which their sense of self dissolves. Is this at all possible?

Motivation for sports and school go hand in hand for adolescent athletes
17 May 2022 at 8:22am
Adolescent athletes with high motivation for school also have high motivation for sports. Male students tend to be less interested in school than their female peers, a new study shows.

Early warning system forecasts who needs critical care for COVID-19
17 May 2022 at 8:22am
An algorithm can accurately predict which hospitalized patients are at the highest risk of death and require critical care, regardless of immune protection status and virus variant.

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammatio...
17 May 2022 at 8:22am
Adenosine triphosphate (ATP) secreted from sensory neuron-interneuron crosstalk is key to the spreading of inflammation across joints, acting as a neurotransmitter and inflammation enhancer.

Desktop air curtain system prevents spread of COVID-19 in hospital settings
17 May 2022 at 8:22am
Researchers have developed a desktop air curtain system that blocks all incoming aerosol particles. An air curtain, or air door, is a fan-powered ventilation system that creates an air seal over an entryway, but one challenge in developing smaller air curtains is fully blocking emitted aerosol particles over time because it is difficult to maintain the air wall over a long distance.

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